You
have been diagnosed as having a tumor (cancer) in your liver. This
cancer may be a primary cancer of the liver itself or a cancer
that has spread to the liver from somewhere else in your body
(metastasized). Chemoembolization is a regional treatment of
the liver for various types of liver cancers. In this treatment,
a highly concentrated dose of chemotherapy drugs are injected
into the artery feeding the tumor, white at the same time, the
artery is plugged up (embolized) by a mixture of oil and tiny
particles. These particles cut off the blood supply to
the tumor and trap the chemotherapy inside the tumor. The
tumor is deprived of food and oxygen and is exposed to a higher
concentration of chemotherapy for a longer period of time than
if the chemotherapy were given in any other way. Also, since
the majority of the chemo stays in the liver you will have very
little systemic side effects.
 |
The
blood supply of the tumor is injected with powerful Chemo
agents & particles choking the tumor of nutrition & Oxygen
as well as bathing the tumor cells with powerful chemotherapeutic
drugs. |
HOW DOES CHEMOEMBOLIZATION WORK?
The
liver is unique in having two blood supplies, an artery (the
hepatic artery) and a large vein (the portal vein). The normal
liver gets about 75% of its blood supply from the portal vein
and only about 25% of its blood supply from the hepatic artery.
When a tumor grows within the liver, it receives virtually all
of its blood supply from the hepatic artery. Therefore, a concentrated
dose of chemotherapeutic drugs injected into the hepatic artery
reaches the tumor directly, sparing most of the liver tissue.
When the artery is blocked, nearly all of the blood supply is
taken away from the tumor, depriving it of nutrients and oxygen.
The tumor remains bathed in the drug for an extended period while
the liver continues to be supplied by blood from the portal vein.
The procedure accomplishes three things:
The procedure accomplishes four things:
|
1. |
Delivers
very high concentration of chemo directly to the tumor. |
|
2. |
Deprives
the tumor of oxygen and nutrients once the blood supply
is blocked. |
|
3. |
By
blocking the hepatic artery, no blood washes through the
tumor. As a result, the drugs bathe the tumor cells for
a longer time. |
|
4. |
Because
the chemo drugs are trapped in the liver there is a decrease
in side effects to the rest of the body. |